SCHEMBL25517604

SCHEMBL25517604

CC(C)(C)OC(=O)N1CC(Oc2ccc(CO)cc2)C1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 6/20 0.50
USP30 Q70CQ3 1/20 0.50
NR1H2 P55055 1/20 0.46
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
NAMPT P43490 1/20 0.42
PDE4B Q07343 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CHEK2 O96017 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3342716 0.87 GPR119 (0.66) GPR119USP30PDE4BALDH1A1CHEK2
SCHEMBL10190106 0.86 USP30 (0.55) GPR119USP30PDE4BALDH1A1CHEK2
SCHEMBL24793305 0.85 USP30 (0.49) GPR119USP30NR1H2NAMPTPDE4B
SCHEMBL28670992 0.85 USP30 (0.53) GPR119USP30NR1H2NAMPTALDH1A1
SCHEMBL6182215 0.85 USP30 (0.53) GPR119USP30NR1H2ALDH1A1CHEK2
SCHEMBL12788093 0.85 USP30 (0.53) GPR119USP30NR1H2ALDH1A1CHEK2
SCHEMBL321227 0.84 KCNH2 (0.54) GPR119USP30
SCHEMBL3343250 0.83 USP30 (0.52) GPR119USP30NR1H2ALDH1A1CHEK2
SCHEMBL16434828 0.83 USP30 (0.52) GPR119USP30ALDH1A1
SCHEMBL14862587 0.83 USP30 (0.52) GPR119USP30NR1H2NAMPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF Shenzhen Bay Laboratory (CN) 2023-05-25 US disclosed
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF Shenzhen Bay Laboratory (CN) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF SSB, EBNA1BP2, PML GPR119 4354/4885USP30 740/4885NR1H2 2055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.