Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 13/20 | 0.66 |
| ▸ | GRN | P28799 | 1/20 | 0.58 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.58 |
| ▸ | CYP51A1 | Q16850 | 3/20 | 0.55 |
| ▸ | REN | P00797 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28951693 | 1.00 | PYGL (0.66) | PYGLGRNSORT1CYP51A1REN | |
| SCHEMBL25517761 | 0.89 | PYGL (0.65) | PYGLCYP51A1REN | |
| SCHEMBL28951200 | 0.89 | PYGL (0.65) | PYGLCYP51A1REN | |
| SCHEMBL30174883 | 0.86 | CCKBR (0.61) | PYGLGRNSORT1CYP51A1REN | |
| SCHEMBL25517406 | 0.86 | CCKBR (0.61) | PYGLGRNSORT1CYP51A1REN | |
| SCHEMBL25224163 | 0.86 | CCKBR (0.61) | PYGLGRNSORT1CYP51A1REN | |
| SCHEMBL25194705 | 0.86 | CCKBR (0.61) | PYGLGRNSORT1CYP51A1REN | |
| SCHEMBL26118536 | 0.80 | CYP51A1 (0.58) | PYGLCYP51A1 | |
| SCHEMBL26118533 | 0.80 | CYP51A1 (0.58) | PYGLCYP51A1 | |
| SCHEMBL25207074 | 0.80 | PYGL (0.47) | PYGLCYP51A1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | COCRYSTAL PHARMA, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | COCRYSTAL PHARMA, INC. | 2023-05-25 | — | — | US | disclosed |
| EP-4132944-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | Cocrystal Pharma, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| CN-115698035-A | Inhibitors of norovirus and coronavirus replication | 共晶制药公司 | 2023-02-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | VIM, ACE, ACE2 | PYGL 889/4885GRN 2468/4885SORT1 4606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.