SCHEMBL25518928

SCHEMBL25518928

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nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 1/20 0.54
LGALS3 P17931 1/20 0.54
LGALS4 P56470 1/20 0.54
TYR P14679 6/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
AMY1A P0DUB6 1/20 0.48
AMY2A P04746 1/20 0.44
GJA1 P17302 1/20 0.44
GJB2 P29033 1/20 0.44
CYP2C9 P11712 1/20 0.44
TSHR P16473 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23640199 1.00 LGALS8 (0.54) LGALS8LGALS3LGALS4TYRMEN1
SCHEMBL20150990 1.00 LGALS8 (0.54) LGALS8LGALS3LGALS4TYRMEN1
SCHEMBL11946920 1.00 LGALS8 (0.54) LGALS8LGALS3LGALS4TYRMEN1
SCHEMBL19660113 1.00 LGALS8 (0.54) LGALS8LGALS3LGALS4TYRMEN1
SCHEMBL18158171 1.00 LGALS8 (0.54) LGALS8LGALS3LGALS4TYRMEN1
SCHEMBL22869842 0.93 LGALS8 (0.53) LGALS8LGALS3LGALS4TYRMEN1
SCHEMBL19296379 0.92 LGALS8 (0.47) LGALS8LGALS3LGALS4TYRMEN1
SCHEMBL23030288 0.92 LGALS8 (0.47) LGALS8LGALS3LGALS4TYRMEN1
SCHEMBL22869799 0.91 LGALS8 (0.52) LGALS8LGALS3LGALS4TYRMEN1
SCHEMBL22869557 0.91 LGALS8 (0.52) LGALS8LGALS3LGALS4TYRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11649475-B2 Dioxetane compounds and their use for the detection of microorganisms RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11649475-B2 Dioxetane compounds and their use for the detection of microorganisms DAXX, LITAF, EDF1 LGALS8 1274/4885LGALS3 738/4885LGALS4 346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.