Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14634616 | 0.85 | GPR119 (0.45) | GPR119 | |
| SCHEMBL14634615 | 0.85 | GPR119 (0.45) | GPR119 | |
| SCHEMBL20147451 | 0.83 | HRH3 (0.52) | HRH3GPR119 | |
| SCHEMBL2555295 | 0.81 | HRH3 (0.50) | HRH3GPR119 | |
| SCHEMBL14634789 | 0.80 | GPR119 (0.72) | GPR119 | |
| SCHEMBL14634788 | 0.80 | GPR119 (0.72) | GPR119 | |
| SCHEMBL22663355 | 0.80 | PDGFRB (0.36) | GPR119 | |
| SCHEMBL15648405 | 0.79 | TDO2 (0.42) | HRH3GPR119 | |
| SCHEMBL2553243 | 0.78 | GPR119 (0.50) | GPR119 | |
| SCHEMBL2553246 | 0.78 | GPR119 (0.50) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556056-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011127051-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2011-10-13 | — | — | WO | disclosed |