Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2246879 | 1.00 | HRH3 (0.40) | HRH3CCR1GAA | |
| SCHEMBL2246972 | 0.92 | HRH3 (0.38) | HRH3 | |
| SCHEMBL2551755 | 0.92 | HRH3 (0.38) | HRH3 | |
| SCHEMBL2245928 | 0.87 | NPC1 (0.47) | HRH3 | |
| SCHEMBL2546594 | 0.87 | NPC1 (0.47) | HRH3 | |
| SCHEMBL2552704 | 0.82 | LMNA (0.42) | GAA | |
| SCHEMBL2249244 | 0.82 | LMNA (0.42) | GAA | |
| SCHEMBL2253954 | 0.81 | NPC1 (0.50) | — | |
| SCHEMBL2248062 | 0.79 | KDM4E (0.55) | GAA | |
| SCHEMBL2252896 | 0.79 | KDM4E (0.55) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263628-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2011-10-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263628-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | HNMT, HCAR2, HPGD | HRH3 18/4885CCR1 1292/4885GAA 2031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.