Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK1 | Q8N5S9 | 3/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.36 |
| ▸ | RET | P07949 | 7/20 | 0.32 |
| ▸ | KIF5B | P33176 | 7/20 | 0.32 |
| ▸ | KDR | P35968 | 7/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.32 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9973639 | 0.81 | CAMKK1 (0.34) | CAMKK1CAMKK2EGFRIRAK4 | |
| SCHEMBL1011251 | 0.80 | IRAK4 (0.39) | RETKIF5BKDRRIPK2EGFR | |
| SCHEMBL25552038 | 0.77 | EGFR (0.40) | RETKIF5BKDRRPS6KA3IKBKE | |
| SCHEMBL24037705 | 0.77 | KDR (0.41) | RETKIF5BKDRRIPK2EGFR | |
| SCHEMBL25521668 | 0.75 | EGFR (0.31) | CAMKK1CAMKK2RETKIF5BKDR | |
| SCHEMBL15971471 | 0.74 | IRAK4 (0.40) | RETKIF5BKDRRIPK2EGFR | |
| SCHEMBL3320604 | 0.74 | RET (0.31) | RETKIF5BKDRRIPK2EGFR | |
| SCHEMBL13195987 | 0.74 | MAP4K4 (0.41) | RETKIF5BKDRRIPK2EGFR | |
| SCHEMBL22323303 | 0.73 | TRPA1 (0.50) | RETKIF5BKDRRIPK2EGFR | |
| SCHEMBL6962702 | 0.72 | RPS6KA3 (0.36) | CAMKK1CAMKK2RPS6KA3EIF4A3IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |