Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23754028 | 0.88 | ERN1 (0.32) | ALDH1A1SMN1; SMN2KIF11 | |
| SCHEMBL48658 | 0.83 | CES2 (0.42) | ALDH1A1SMN1; SMN2KIF11CES2CES1 | |
| SCHEMBL24981909 | 0.78 | ERN1 (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL23769421 | 0.78 | SRC (0.39) | ALDH1A1 | |
| SCHEMBL16584916 | 0.78 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2KIF11 | |
| SCHEMBL18002614 | 0.73 | KDM4E (0.46) | ALDH1A1SMN1; SMN2CES2CES1 | |
| SCHEMBL19125728 | 0.73 | SRC (0.41) | ALDH1A1SMN1; SMN2KIF11 | |
| SCHEMBL19748916 | 0.73 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2KIF11CES2CES1 | |
| SCHEMBL1613502 | 0.73 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KIF11 | |
| SCHEMBL19136810 | 0.73 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180436-A1 | TRICYCLIC PYRIMIDINONE COMPOUND, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | Neusco Biotech Limited (CN) | 2023-05-17 | — | — | EP | disclosed |
| EP-4174070-A1 | TRICYCLIC PYRIMIDINONE COMPOUND, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | Neusco Biotech Limited (CN) | 2023-05-03 | — | — | EP | disclosed |