Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700394 | 0.79 | HCAR3 (0.39) | KMT2AL3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL30700598 | 0.79 | F2 (0.48) | KMT2AL3MBTL1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL25564432 | 0.78 | HTT (0.34) | KMT2AL3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL12110034 | 0.76 | KMT2A (0.60) | KMT2AL3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL25530092 | 0.75 | ALDH1A1 (0.35) | KMT2AL3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL25856053 | 0.75 | KMT2A (0.34) | KMT2AL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL28742951 | 0.74 | KMT2A (0.39) | KMT2AL3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL7948229 | 0.71 | KMT2A (0.60) | KMT2AL3MBTL1NPC1RAB9ACYP2D6 | |
| SCHEMBL22549347 | 0.71 | BRD4 (0.42) | KMT2AL3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL31467455 | 0.71 | PLK1 (0.38) | KMT2AL3MBTL1NPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| EP-4183783-A1 | IMMUNOMODULATOR | Hitgen Inc. (CN) | 2023-05-24 | — | — | EP | disclosed |