Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.38 |
| ▸ | ESR1 | P03372 | 9/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523361 | 0.94 | MEN1 (0.39) | DHODHESR1ESR2MEN1KMT2A | |
| SCHEMBL25520070 | 0.83 | MEN1 (0.40) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL25520067 | 0.82 | MEN1 (0.32) | DHODHESR1ESR2MEN1KMT2A | |
| SCHEMBL25522431 | 0.80 | ESR1 (0.39) | DHODHESR1ESR2ALDH1A1GAA | |
| SCHEMBL25522215 | 0.78 | ESR1 (0.40) | ESR1ESR2MEN1KMT2A | |
| SCHEMBL25521407 | 0.77 | AAK1 (0.32) | DHODHMEN1KMT2A | |
| SCHEMBL25519643 | 0.72 | CASP3 (0.39) | DHODHGAA | |
| SCHEMBL25520053 | 0.71 | ESR1 (0.43) | DHODHESR1ESR2MEN1KMT2A | |
| SCHEMBL25522210 | 0.69 | KDM4E (0.42) | L3MBTL1 | |
| SCHEMBL28760330 | 0.67 | ESR1 (0.57) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |