Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25520063 | 0.93 | KDM4E (0.46) | KDM4EPARP1L3MBTL1NR1H2NR1H3 | |
| SCHEMBL25521932 | 0.83 | KDM4E (0.49) | KDM4EPARP1L3MBTL1NR1H2NR1H3 | |
| SCHEMBL25522207 | 0.81 | ABCG2 (0.40) | KDM4EL3MBTL1GRIN2BABCB1ABCG2 | |
| SCHEMBL25522339 | 0.80 | KDM4E (0.40) | KDM4EPARP1L3MBTL1CYP11B2GRIN2B | |
| SCHEMBL25522331 | 0.78 | L3MBTL1 (0.50) | KDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL25521675 | 0.75 | ABCG2 (0.42) | KDM4EL3MBTL1GRIN2BABCB1ABCG2 | |
| SCHEMBL25523414 | 0.74 | KDM4E (0.51) | KDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL25522217 | 0.72 | RPS6KA3 (0.35) | KDM4EHSD17B1HSD17B2 | |
| SCHEMBL23717257 | 0.71 | PSMD14 (0.42) | KDM4EPARP1GRIN2BNR1H2NR1H3 | |
| SCHEMBL31010855 | 0.70 | NPC1 (0.47) | KDM4EL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |