Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.53 |
| ▸ | KDM5C | P41229 | 7/20 | 0.53 |
| ▸ | KDM4A | O75164 | 7/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.53 |
| ▸ | KDM3A | Q9Y4C1 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | KDM6B | O15054 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.51 |
| ▸ | UNG | P13051 | 1/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.49 |
| ▸ | KDM4B | O94953 | 3/20 | 0.49 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.48 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 4/20 | 0.47 |
| ▸ | TET3 | O43151 | 1/20 | 0.47 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29141532 | 0.86 | KMO (0.57) | KMOLOXL2KDM4CKDM5CKDM4A | |
| SCHEMBL30772303 | 0.86 | KMO (0.57) | KMOLOXL2KDM4CKDM5CKDM4A | |
| SCHEMBL6968107 | 0.86 | MAP4K4 (0.51) | KMOLOXL2KDM5CALDH1A1KDM5B | |
| SCHEMBL12970207 | 0.83 | KDM5C (0.60) | KMOKDM4CKDM5CKDM4AKDM2A | |
| SCHEMBL15329552 | 0.83 | UNG (0.63) | KMOKDM4CKDM5CKDM4AKDM2A | |
| SCHEMBL29541336 | 0.81 | KDM4C (0.71) | KMOKDM4CKDM5CKDM4AKDM2A | |
| SCHEMBL648273 | 0.81 | KDM4C (0.71) | KMOKDM4CKDM5CKDM4AKDM2A | |
| SCHEMBL3713431 | 0.81 | KDM4E (0.58) | LOXL2KDM4CKDM5CKDM2AKDM3A | |
| SCHEMBL23303939 | 0.81 | KMO (0.67) | KMOLOXL2KDM4CKDM5CKDM4A | |
| SCHEMBL30318846 | 0.81 | KMO (0.67) | KMOLOXL2KDM4CKDM5CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |