Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 1/20 | 0.63 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.59 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.59 |
| ▸ | KMO | O15229 | 3/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KDM5C | P41229 | 3/20 | 0.53 |
| ▸ | KDM4A | O75164 | 3/20 | 0.53 |
| ▸ | KDM6B | O15054 | 2/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.53 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.53 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952036 | 0.86 | UNG (0.79) | UNGTRIM24TRIM33KMOKDM4E | |
| SCHEMBL2587878 | 0.86 | UNG (0.79) | UNGTRIM24TRIM33KMOKDM4E | |
| SCHEMBL2552275 | 0.83 | KMO (0.59) | UNGKMOKDM4CKDM4EKDM5C | |
| SCHEMBL12970207 | 0.83 | KDM5C (0.60) | UNGKMOKDM4CKDM4EKDM5C | |
| SCHEMBL27717106 | 0.81 | KMO (0.73) | KMOKDM4CKDM4EKDM5CKDM4A | |
| SCHEMBL29541336 | 0.81 | KDM4C (0.71) | KMOKDM4CKDM4EKDM5CKDM4A | |
| SCHEMBL648273 | 0.81 | KDM4C (0.71) | KMOKDM4CKDM4EKDM5CKDM4A | |
| SCHEMBL21311111 | 0.80 | CA12 (0.59) | KMOKDM4CKDM4EKDM5CKDM4A | |
| SCHEMBL2561069 | 0.80 | KDM4C (0.60) | KMOKDM4CKDM4EKDM5CKDM4A | |
| SCHEMBL2557229 | 0.79 | LDHA (0.64) | UNGTRIM24TRIM33ERN1P4HA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |