Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30676086 | 1.00 | IKBKB (0.37) | IKBKBTDP1GAAMAPTSMN1; SMN2 | |
| SCHEMBL7023474 | 0.79 | NOS2 (0.44) | NOS2NOS3NOS1TSHRALDH1A1 | |
| SCHEMBL8560653 | 0.76 | MEN1 (0.37) | TDP1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28135777 | 0.75 | HCAR2 (0.36) | SMN1; SMN2TLR7TSHRHCAR3ALDH1A1 | |
| SCHEMBL28076490 | 0.75 | TLR7 (0.41) | IKBKBTDP1GAASMN1; SMN2NOS2 | |
| SCHEMBL28043957 | 0.74 | NOS2 (0.44) | IKBKBTDP1MAPTNOS2NOS3 | |
| SCHEMBL3064440 | 0.74 | NOS2 (0.42) | TDP1GAAMAPTSMN1; SMN2NOS2 | |
| SCHEMBL15923846 | 0.73 | TSHR (0.38) | TDP1GAAMAPTSMN1; SMN2NOS1 | |
| SCHEMBL17335193 | 0.73 | CYP2C9 (0.38) | SMN1; SMN2NOS1TSHRALDH1A1LMNA | |
| SCHEMBL6031561 | 0.70 | NOS2 (0.44) | IKBKBNOS2NOS3NOS1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566637-B | GLP-1 receptor agonists and uses thereof | 辉瑞公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-112566637-A | GLP-1 receptor agonists and uses thereof | 辉瑞公司 | 2021-03-26 | — | — | CN | disclosed |
| EP-2552208-A1 | IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS | Glaxo Group Limited (GB) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011123609-A1 | IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2011-10-06 | — | — | WO | disclosed |