Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MGMT | P16455 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572912 | 0.79 | MGMT (0.39) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL8597378 | 0.79 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL28203110 | 0.78 | MEN1 (0.40) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL8565117 | 0.77 | MAPT (0.39) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL8568162 | 0.76 | MEN1 (0.38) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL2552279 | 0.76 | IKBKB (0.37) | MAPTALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL30676086 | 0.76 | IKBKB (0.37) | MAPTALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL30622686 | 0.73 | MEN1 (0.45) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL1959760 | 0.73 | MEN1 (0.45) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL8561983 | 0.73 | ALDH1A1 (0.50) | MEN1KMT2AMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |