Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25524009 | 0.83 | KDM4E (0.53) | KDM4EKMT2AMMP2PIM1TDP1 | |
| SCHEMBL9907329 | 0.77 | KDM4E (0.62) | KDM4EKMT2AMMP2PIM1TDP1 | |
| SCHEMBL1724445 | 0.75 | KDM4E (0.49) | KDM4EKMT2AMMP2TDP1MGAM | |
| SCHEMBL25523412 | 0.75 | AHR (0.35) | KDM4EKMT2ARAB9A | |
| SCHEMBL24453816 | 0.73 | KDM4E (0.60) | KDM4EKMT2AMMP2PIM1TDP1 | |
| SCHEMBL171491 | 0.72 | KDM4E (1.00) | KDM4EKMT2AMMP2PIM1TDP1 | |
| SCHEMBL29697210 | 0.72 | KDM4E (1.00) | KDM4EKMT2AMMP2PIM1TDP1 | |
| SCHEMBL11121278 | 0.71 | KDM4E (0.90) | KDM4EKMT2AMMP2PIM1TDP1 | |
| SCHEMBL29932233 | 0.71 | KDM4E (0.96) | KDM4EKMT2AMMP2PIM1TDP1 | |
| SCHEMBL28949889 | 0.71 | KDM4E (0.96) | KDM4EKMT2AMMP2PIM1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |