Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25522217 | 0.95 | RPS6KA3 (0.35) | AHRRPS6KA3CASRADORA3ADORA1 | |
| SCHEMBL25521794 | 0.82 | KDM4E (0.39) | KDM4EHSD17B1HSD17B2AKR1C3AKR1C2 | |
| SCHEMBL25520071 | 0.78 | ENPP1 (0.34) | AHRRPS6KA3CASRKDM4EHSD17B1 | |
| SCHEMBL25522344 | 0.76 | CASR (0.36) | CASRHSD17B1HSD17B2MEN1KMT2A | |
| SCHEMBL25523538 | 0.75 | KDM4E (0.55) | KDM4ERAB9AKMT2A | |
| SCHEMBL25519641 | 0.74 | GABRA1 (0.44) | RPS6KA3KDM4EL3MBTL1 | |
| SCHEMBL25523414 | 0.72 | KDM4E (0.51) | ADORA3ADORA1KDM4ENPC1RAB9A | |
| SCHEMBL25521412 | 0.70 | PIK3CD (0.42) | RPS6KA3KDM4EL3MBTL1 | |
| SCHEMBL25521416 | 0.70 | AKR1C3 (0.45) | KDM4EAKR1C3AKR1C2NPC1RAB9A | |
| SCHEMBL25523475 | 0.69 | KDM4E (0.44) | KDM4ENPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |