Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 4/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM5C | P41229 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | KDM6B | O15054 | 2/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.35 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 2/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.35 |
| ▸ | TET3 | O43151 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220172 | 0.81 | KDM1A (0.44) | KDM1AHDAC1HDAC6IDO1AR | |
| SCHEMBL30595888 | 0.81 | KDM1A (0.44) | KDM1AHDAC1HDAC6IDO1AR | |
| SCHEMBL3466541 | 0.81 | IDO1 (0.41) | KDM1AHDAC1HDAC6IDO1AR | |
| Bromide SCHEMBL6203968 | 0.79 | KDM1A (0.42) | KDM1AHDAC1HDAC6IDO1AR | |
| SCHEMBL25263407 | 0.79 | KDM1A (0.42) | KDM1AHDAC1HDAC6IDO1AR | |
| SCHEMBL28786825 | 0.77 | LMNA (0.47) | KDM1AHDAC1HDAC6IDO1AR | |
| SCHEMBL3465859 | 0.77 | IDO1 (0.39) | KDM1AHDAC1HDAC6IDO1AR | |
| SCHEMBL3124147 | 0.75 | KDM1A (0.40) | KDM1AHDAC1HDAC6IDO1AR | |
| SCHEMBL40395 | 0.75 | KDM4C (0.61) | KDM1AHDAC1HDAC6KDM4CKDM4E | |
| SCHEMBL30527973 | 0.75 | KDM4C (0.61) | KDM1AHDAC1HDAC6KDM4CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |