SCHEMBL40395

SCHEMBL40395

O=C(O)c1ccnc(Br)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 8/20 0.61
KDM5C P41229 6/20 0.61
KDM4E B2RXH2 5/20 0.61
KDM4A O75164 5/20 0.61
KDM2A Q9Y2K7 5/20 0.61
KDM3A Q9Y4C1 5/20 0.61
KDM5B Q9UGL1 5/20 0.61
KDM6B O15054 4/20 0.61
KDM5A P29375 3/20 0.61
KDM4D Q6B0I6 3/20 0.61
ALDH1A1 P00352 2/20 0.61
TET3 O43151 1/20 0.61
BBOX1 O75936 1/20 0.61
MAPT P10636 1/20 0.61
ASPH Q12797 1/20 0.61
TET2 Q6N021 1/20 0.61
ALKBH5 Q6P6C2 1/20 0.61
KDM7A Q6ZMT4 1/20 0.61
KDM8 Q8N371 1/20 0.61
TET1 Q8NFU7 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30527973 1.00 KDM4C (0.61) KDM4CKDM5CKDM4EKDM4AKDM2A
Hydrochloric Acid SCHEMBL29188716 0.98 KDM4C (0.59) KDM4CKDM5CKDM4EKDM4AKDM2A
Formaldehyde SCHEMBL27828603 0.96 KDM4C (0.57) KDM4CKDM5CKDM4EKDM4AKDM2A
Nitrous Acid SCHEMBL28404954 0.92 KDM4C (0.53) KDM4CKDM5CKDM4EKDM4AKDM2A
SCHEMBL28786825 0.84 LMNA (0.47) KDM4CKDM5CKDM4EKDM4AKDM2A
SCHEMBL25263407 0.83 KDM1A (0.42) KDM4CKDM5CKDM4EKDM4AKDM2A
SCHEMBL2430356 0.81 KDM1A (0.44) KDM4CKDM5CKDM4EKDM4AKDM2A
SCHEMBL3127472 0.81 PARP1 (0.48) KDM4CKDM5CKDM4EKDM4AKDM2A
SCHEMBL1137138 0.81 KDM1A (0.44) KDM4CKDM5CKDM4EKDM4AKDM2A
SCHEMBL31026889 0.81 PARP1 (0.48) KDM4CKDM5CKDM4EKDM4AKDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 846 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119753728-A Preparation method of ordered defective indium cluster frame porous material for electrocatalytic conversion of carbon dioxide to urea 东北师范大学 2025-04-04 CN claimed
CN-114555584-B Ai Funi cloth (IVOSIDENIB) and process for producing intermediate thereof 法国施维雅药厂 2024-07-05 CN claimed
CN-116854720-A Isonicacid chelated aluminum oxide cluster compound, and macro preparation method and application thereof 闽都创新实验室 2023-10-10 CN claimed
WO-2023131951-A1 NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2023-07-13 WO claimed
WO-2023019912-A9 BENZOTRIAZINE DIOXIDE AND PHARMACEUTICAL COMPOSITION THEREOF 杭州瑞臻医药有限公司 2023-06-01 WO claimed
CN-115850244-B Preparation method of topiroxostat 成都大学 2023-05-16 CN claimed
CN-115850244-A Preparation method of topiroxostat 成都大学 2023-03-28 CN claimed
CN-115724793-A Preparation method of 2-bromoisonicotinic acid nitrile 山西永津集团有限公司 2023-03-03 CN claimed
WO-2023019912-A1 BENZOTRIAZINE DIOXIDE AND PHARMACEUTICAL COMPOSITION THEREOF 杭州瑞臻医药有限公司 2023-02-23 WO claimed
CN-114555584-A Process for the preparation of ivonib (IVOSIDENIB) and intermediates thereof 法国施维雅药厂 2022-05-27 CN claimed
EP-3364967-B1 FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2026-05-20 EP disclosed
WO-2025090928-A9 COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES AQUINNAH PHARMACEUTICALS, INC. (US) 2026-04-30 WO disclosed
WO-2026085629-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF Université de Montréal (CA) 2026-04-30 WO disclosed
EP-4709716-A1 ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF GENZYME CORPORATION (US) 2026-03-18 EP disclosed
EP-4702025-A1 BICYCLIC HETEROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER F. Hoffmann-La Roche AG (CH) 2026-03-04 EP disclosed
US-4977267-A ANTISECRETORY AGENT FUJIREBIO KABUSHIKI KAISHA (JP) 1990-12-11 US disclosed
US-4921867-A Pyridine compounds useful for therapy or prophylaxis of a disease associated with airway obstruction GLAXO GROUP LIMITED (GB) 1990-05-01 US disclosed
US-4912101-A Containing a secondary amide, suflur group and a furan ring FUJIREBIO KABUSHIKI KAISHA (JP) 1990-03-27 US disclosed
EP-0282077-A2 Pyridyloxy derivatives FUJIREBIO KABUSHIKI KAISHA (JP) 1988-09-14 EP disclosed
EP-0278728-A2 1-(4-Amino-3,5-dichlorophenyl)-2-(substituted amino)ethanol derivatives and their use in the treatment of respiratory disease GLAXO GROUP LIMITED (GB) 1988-08-17 EP disclosed