Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | METAP1 | P53582 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28809132 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTCYP3A4NPC1 | |
| SCHEMBL247478 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTCYP3A4NPC1 | |
| SCHEMBL29364156 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTCYP3A4NPC1 | |
| SCHEMBL13403464 | 0.73 | HDAC8 (0.43) | ALDH1A1KDM4EMAPTNPC1POLB | |
| SCHEMBL240893 | 0.71 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTCYP3A4NCF1 | |
| SCHEMBL9317055 | 0.71 | ALDH1A1 (0.38) | ALDH1A1RAB9ANCF1TSHR | |
| Bromide SCHEMBL7758538 | 0.69 | ALDH1A1 (0.37) | ALDH1A1KDM4ENCF1LMNATSHR | |
| SCHEMBL6512973 | 0.69 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTCYP3A4NPC1 | |
| Iodide SCHEMBL9646548 | 0.69 | ALDH1A1 (0.37) | ALDH1A1KDM4EMAPTCYP3A4RAB9A | |
| SCHEMBL25342075 | 0.69 | BCHE (0.42) | ALDH1A1KDM4EMAPTNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | ALDH1A1 3447/4885KDM4E 1835/4885MAPT 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.