Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12015723 | 0.83 | PIK3CD (0.50) | SIGMAR1OPRM1KCNH2ACHEHDAC1 | |
| SCHEMBL9424540 | 0.83 | PIK3CD (0.50) | SIGMAR1OPRM1KCNH2ACHEHDAC1 | |
| SCHEMBL12169472 | 0.83 | PIK3CD (0.50) | SIGMAR1OPRM1KCNH2ACHEHDAC1 | |
| SCHEMBL26745631 | 0.81 | LTA4H (0.49) | PIK3CD | |
| SCHEMBL26745601 | 0.81 | LTA4H (0.49) | PIK3CD | |
| SCHEMBL2134022 | 0.80 | HDAC1 (0.46) | SIGMAR1OPRM1KCNH2ACHEHDAC1 | |
| Hydrochloric Acid SCHEMBL7937361 | 0.79 | HDAC1 (0.48) | SIGMAR1OPRM1KCNH2ACHEHDAC1 | |
| Hydrochloric Acid SCHEMBL7927508 | 0.79 | HDAC1 (0.48) | SIGMAR1OPRM1KCNH2ACHEHDAC1 | |
| Hydrochloric Acid SCHEMBL7927437 | 0.79 | HDAC1 (0.48) | SIGMAR1OPRM1KCNH2ACHEHDAC1 | |
| SCHEMBL14177604 | 0.79 | HSD11B1 (0.55) | SIGMAR1OPRM1KCNH2ACHEHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | COCRYSTAL PHARMA, INC. | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | VIM, ACE, ACE2 | SIGMAR1 1887/4885OPRM1 1969/4885KCNH2 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.