Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 11/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19262601 | 0.89 | APP (0.44) | — | |
| SCHEMBL19262698 | 0.89 | APP (0.44) | — | |
| SCHEMBL254675 | 0.87 | APP (0.39) | ANPEP | |
| SCHEMBL15235772 | 0.87 | APP (0.39) | ANPEP | |
| SCHEMBL15235688 | 0.87 | APP (0.39) | ANPEP | |
| SCHEMBL157159 | 0.87 | APP (0.39) | ANPEP | |
| SCHEMBL10272727 | 0.80 | CA2 (0.47) | ANPEPCA1CA2HPGDS | |
| SCHEMBL1109169 | 0.80 | CA2 (0.47) | ANPEPCA1CA2HPGDS | |
| SCHEMBL1109123 | 0.80 | CA2 (0.47) | ANPEPCA1CA2HPGDS | |
| SCHEMBL403655 | 0.80 | HPGDS (0.59) | ANPEPCA1CA2HPGDSHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031298-A2 | ETHYNYLBENZENE DERIVATIVES | DUKE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |