Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22125651 | 0.85 | L3MBTL1 (0.35) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL24068085 | 0.85 | KDM4E (0.35) | PDE10ANPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL25948856 | 0.80 | NOS3 (0.34) | L3MBTL1 | |
| SCHEMBL24068092 | 0.78 | SMN1; SMN2 (0.46) | NPC1MAPTRAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL22125652 | 0.78 | TTR (0.32) | — | |
| SCHEMBL24068039 | 0.76 | SMN1; SMN2 (0.39) | NPC1MAPTRAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL23114459 | 0.69 | HDAC8 (0.42) | PDE10ANPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL19781524 | 0.69 | L3MBTL1 (0.49) | L3MBTL1HSD17B10 | |
| SCHEMBL20600772 | 0.67 | L3MBTL1 (0.35) | L3MBTL1HSD17B10 | |
| SCHEMBL14431560 | 0.67 | NPC1 (0.32) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091604-A1 | ADENOSINE RECEPTOR ANTAGONISTS | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |