Unoprostone Isopropyl

Unoprostone Isopropyl

SCHEMBL2552761

CCCCCCCC(=O)CC[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@@H](O)C[C@H]1O.CCCCCCCC(=O)CC[C@@H]1[C@@H](C/C=C\CCCC(=O)OC(C)C)[C@@H](O)C[C@H]1O

nearest known ligand 0.92

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.92
ADORA3 P0DMS8 1/20 0.92
ADRA2C P18825 1/20 0.92
SLC6A2 P23975 1/20 0.92
HTR2B P41595 1/20 0.92
MC3R P41968 1/20 0.92
SLC6A3 Q01959 1/20 0.92
PDE4D Q08499 1/20 0.92
SCN5A Q14524 1/20 0.92
PTGFR P43088 5/20 0.55
KDM4E B2RXH2 2/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
MAPK1 P28482 2/20 0.55
ABCB11 O95342 1/20 0.55
MAPT P10636 1/20 0.55
TBXA2R P21731 5/20 0.51
LMNA P02545 5/20 0.51
ALDH1A1 P00352 4/20 0.51
SLCO2A1 Q92959 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Unoprostone Isopropyl SCHEMBL22965374 0.96 PDE4D (1.00) PGRADORA3ADRA2CSLC6A2HTR2B
Unoprostone Isopropyl SCHEMBL192726 0.96 PDE4D (1.00) PGRADORA3ADRA2CSLC6A2HTR2B
Unoprostone Isopropyl SCHEMBL14674258 0.96 PDE4D (1.00) PGRADORA3ADRA2CSLC6A2HTR2B
Unoprostone Isopropyl SCHEMBL7562527 0.96 PDE4D (1.00) PGRADORA3ADRA2CSLC6A2HTR2B
Unoprostone Isopropyl SCHEMBL5971186 0.96 PDE4D (1.00) PGRADORA3ADRA2CSLC6A2HTR2B
SCHEMBL7617448 0.94 PDE4D (0.96) PGRADORA3ADRA2CSLC6A2HTR2B
SCHEMBL7617442 0.94 PDE4D (0.96) PGRADORA3ADRA2CSLC6A2HTR2B
SCHEMBL6409062 0.90 PGR (0.73) PGRADORA3ADRA2CSLC6A2HTR2B
Unoprostone SCHEMBL22965277 0.90 PGR (0.73) PGRADORA3ADRA2CSLC6A2HTR2B
Unoprostone SCHEMBL2469329 0.90 PGR (0.73) PGRADORA3ADRA2CSLC6A2HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2555994-A1 DELIVERY SYSTEM FOR DISPENSING METERED VOLUMES OF PURE OR STERILE FLOWABLE SUBSTANCES Reseal International Limited Partnership (US) 2013-02-13 EP disclosed
WO-2011126569-A1 DELIVERY SYSTEM FOR DISPENSING METERED VOLUMES OF PURE OR STERILE FLOWABLE SUBSTANCES RESEAL INTERNATIONAL LIMITED PARTNERSHIP (US) 2011-10-13 WO disclosed