Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2552771 | 1.00 | SIGMAR1 (0.47) | SIGMAR1DRD2HTR2AMEN1KMT2A | |
| SCHEMBL25642148 | 0.99 | SIGMAR1 (0.46) | SIGMAR1DRD2HTR2AMEN1KMT2A | |
| SCHEMBL2550296 | 0.99 | SIGMAR1 (0.46) | SIGMAR1DRD2HTR2AMEN1KMT2A | |
| SCHEMBL2550291 | 0.99 | SIGMAR1 (0.46) | SIGMAR1DRD2HTR2AMEN1KMT2A | |
| SCHEMBL2557457 | 0.91 | SIGMAR1 (0.39) | SIGMAR1DRD2HTR2AMEN1KMT2A | |
| SCHEMBL2557456 | 0.91 | SIGMAR1 (0.39) | SIGMAR1DRD2HTR2AMEN1KMT2A | |
| SCHEMBL25272743 | 0.89 | HTR2A (0.49) | SIGMAR1DRD2HTR2AMEN1KMT2A | |
| SCHEMBL25643695 | 0.89 | HTR2A (0.49) | SIGMAR1DRD2HTR2AMEN1KMT2A | |
| SCHEMBL25642197 | 0.89 | HTR2A (0.49) | SIGMAR1DRD2HTR2AMEN1KMT2A | |
| SCHEMBL25642175 | 0.87 | DRD2 (0.42) | SIGMAR1DRD2HTR2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121055-A1 | PYRIDINYL DERIVATIVES COMPRISING A CYANOGUANIDINE OR SQUARIC ACID MOIETY | TOPOTARGET A/S (DK) | 2011-10-06 | — | — | WO | claimed |