SCHEMBL255282

SCHEMBL255282

N#CC(C#N)=C1CCc2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.55
ALDH1A1 P00352 4/20 0.47
CES1 P23141 1/20 0.43
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.40
SRD5A1 P18405 1/20 0.37
SRD5A2 P31213 1/20 0.37
POLB P06746 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HPGD P15428 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HKDC1 Q2TB90 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ESR1 P03372 1/20 0.35
CYP19A1 P11511 1/20 0.35
ESR2 Q92731 1/20 0.35
CYP2A6 P11509 1/20 0.35
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30067338 1.00 EGFR (0.55) EGFRALDH1A1CES1GAAMAPT
SCHEMBL809325 0.89 CYP2A6 (0.46) EGFRALDH1A1CES1GAAMAPT
SCHEMBL30067479 0.89 CYP2A6 (0.46) EGFRALDH1A1CES1GAAMAPT
SCHEMBL4407899 0.81 CES1 (0.41) EGFRALDH1A1CES1GAAHTT
SCHEMBL30067531 0.80 HSD17B10 (0.51) EGFRALDH1A1CES1GAAMAPT
SCHEMBL254570 0.80 HSD17B10 (0.51) EGFRALDH1A1CES1GAAMAPT
SCHEMBL255344 0.78 EGFR (0.62) EGFRALDH1A1GAAMAPTHTT
SCHEMBL9881029 0.77 CES1 (0.37) EGFRALDH1A1CES1GAAMAPT
SCHEMBL9970451 0.77 CES1 (0.37) EGFRALDH1A1CES1GAAMAPT
SCHEMBL31571396 0.77 CES1 (0.37) EGFRALDH1A1CES1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112218855-B NIR-II emissive luminophores 香港科技大学 2024-01-05 CN claimed
CN-116589456-A AIE phototherapy agent with excellent I-type photodynamic activity and photothermal effect, and preparation method and application thereof 河南大学 2023-08-15 CN claimed
CN-116478127-A Cross-shaped near infrared fluorescent compound and preparation method and application thereof 南方医科大学 2023-07-25 CN claimed
CN-116474159-A Constant-temperature photo-thermal system and application thereof 南开大学 2023-07-25 CN claimed
CN-113292576-B Triphenylamine-based photo-thermal small molecule and preparation method and application thereof 山西大学 2023-05-30 CN claimed
CN-113292576-A Triphenylamine-based photo-thermal small molecule and preparation method and application thereof 山西大学 2021-08-24 CN claimed
CN-113045908-A Lipid drop targeted fluorescent dye and preparation method and application thereof 深圳先进技术研究院 2021-06-29 CN claimed
CN-112218855-A NIR-II-emitting luminophores 香港科技大学 2021-01-12 CN claimed
WO-2019238121-A1 NIR-II EMISSIVE LUMINOGENS THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2019-12-19 WO claimed
EP-1235549-B1 AGENT FOR COLOURING KERATIN CONTAINING FIBRES HENKEL KGAA (DE) 2006-11-29 EP claimed
WO-2003030845-A1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1300135-A1 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1292271-A2 AGENT FOR DYEING FIBRES CONTAINING KERATIN Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-19 EP claimed
EP-1235549-A1 AGENT FOR COLOURING KERATIN CONTAINING FIBRES Henkel Kommanditgesellschaft auf Aktien (DE) 2002-09-04 EP claimed
EP-1199065-A2 Hair dye Henkel Kommanditgesellschaft auf Aktien (DE) 2002-04-24 EP claimed
WO-2001097754-A2 AGENT FOR DYEING FIBRES CONTAINING KERATIN, CONTAINING AT LEAST ONE QUINOXALINE DERIVATIVE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO claimed
WO-2001097762-A1 AGENT FOR COLOURING KERATIN-CONTAINING FIBRES COMPRISING AT LEAST ONE OXOCYCLOPENTENE DERIVATIVE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO claimed
WO-2001089587-A2 AGENTS FOR DYEING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-11-29 WO claimed
WO-2001034106-A1 AGENT FOR COLOURING KERATIN CONTAINING FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-05-17 WO claimed