SCHEMBL255344

SCHEMBL255344

N#CC(C#N)=C1CCc2cc3ccccc3cc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.62
ALDH1A1 P00352 4/20 0.42
GAA P10253 2/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
MAPT P10636 2/20 0.31
HTT P42858 2/20 0.31
TP53 P04637 2/20 0.31
HPGD P15428 2/20 0.31
CASP1 P29466 2/20 0.31
CASP7 P55210 2/20 0.31
HSD17B10 Q99714 2/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
HIF1A Q16665 1/20 0.31
CTSL P07711 1/20 0.30
CTSB P07858 1/20 0.30
CTSK P43235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14412560 0.80 EGFR (0.40) EGFRALDH1A1CYP11B1CYP11B2
SCHEMBL9970453 0.80 EGFR (0.40) EGFRALDH1A1MEN1KMT2A
SCHEMBL7049187 0.78 EGFR (0.38) EGFRALDH1A1GAAMEN1KMT2A
SCHEMBL30067338 0.78 EGFR (0.55) EGFRALDH1A1GAAMEN1KMT2A
SCHEMBL255282 0.78 EGFR (0.55) EGFRALDH1A1GAAMEN1KMT2A
SCHEMBL6285970 0.77 EGFR (1.00) EGFRALDH1A1
SCHEMBL254570 0.75 HSD17B10 (0.51) EGFRALDH1A1GAAMEN1KMT2A
SCHEMBL30067531 0.75 HSD17B10 (0.51) EGFRALDH1A1GAAMEN1KMT2A
SCHEMBL19410119 0.72 EGFR (0.61) EGFRALDH1A1HSD17B10
SCHEMBL24483591 0.71 MAOB (0.57) EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130170016-A1 PHOTOREFRACTIVE DEVICE CONTAINING A CHROMOPHORE-DOPED POLYMER LAYER AND ITS MANUFACTURING METHOD NITTO DENKO CORPORATION (JP) 2013-07-04 US disclosed
US-20130163086-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE BY UTILIZING ELECTROLYTES NITTO DENKO CORPORATION (JP) 2013-06-27 US disclosed
US-20130128339-A1 PHOTOREFRACTIVE COMPOSITION RESPONSIVE TO MULTIPLE LASER WAVELENGTHS ACROSS THE VISIBLE LIGHT SPECTRUM NITTO DENKO CORPORATION (JP) 2013-05-23 US disclosed
WO-2013075050-A1 PHOTOREFRACTIVE DEVICE CONTAINING CARBON NANOTUBE-DOPED POLYMER LAYERS AND ITS MANUFACTURING METHOD NITTO DENKO CORPORATION (JP) 2013-05-23 WO disclosed
EP-1578884-B1 POLYMER, PRODUCING METHOD THEREOF, AND PHOTOREFRACTIVE COMPOSITION NITTO DENKO CORP (JP) 2013-04-24 EP disclosed
US-20120275007-A1 OPTICAL DEVICES FOR MODULATING LIGHT OF PHOTOREFRACTIVE COMPOSITIONS WITH THERMAL CONTROL NITTO DENKO CORPORATION (JP) 2012-11-01 US disclosed
WO-2012112876-A1 PHOTOREFRACTIVE DEVICES HAVING SOL-GEL BUFFER LAYERS AND METHODS OF MANUFACTURING NITTO DENKO CORPORATION (JP) 2012-08-23 WO disclosed
US-8203780-B2 Systems and methods for improving the performance of a photorefractive device NITTO DENKO CORPORATION (JP) 2012-06-19 US disclosed
EP-2261270-B1 Polymer, producing method thereof, and photorefractive composition NITTO DENKO CORP (JP) 2012-05-09 EP disclosed
WO-2012031025-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE BY UTILIZING ELECTROLYTES NITTO DENKO CORPORATION (JP) 2012-03-08 WO disclosed
US-20100060975-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE NITTO DENKO CORPORATION (JP) 2010-03-11 US disclosed
US-20090197186-A1 OPTICAL DEVICES RESPONSIVE TO BLUE LASER AND METHOD OF MODULATING LIGHT NITTO DENKO CORPORATION (JP) 2009-08-06 US disclosed
US-20090052009-A1 NON-LINEAR OPTICAL DEVICE SENSITIVE TO GREEN LASER NITTO DENKO CORPORATION (JP) 2009-02-26 US disclosed
WO-2008091716-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE NITTO DENKO CORPORATION (JP) 2008-07-31 WO disclosed
US-20080039603-A1 NON-LINEAR OPTICAL DEVICE WITH LONG GRATING PERSISTENCY NITTO DENKO CORPORATION (JP) 2008-02-14 US disclosed
WO-2008013774-A2 NON-LINEAR OPTICAL DEVICE WITH LONG GRATING PERSISTENCY NITTO DENKO CORPORATION (JP) 2008-01-31 WO disclosed
WO-2008013775-A2 NON-LINEAR OPTICAL DEVICE SENSITIVE TO GREEN LASER NITTO DENKO CORPORATION (JP) 2008-01-31 WO disclosed
US-7317058-B2 (Meth)acrylate polymer and non-linear optical device material composition NITTO DENKO CORPORATION (JP) 2008-01-08 US disclosed
US-7250121-B2 Non-linear optical device material composition NITTO DENKO CORPORATION (JP) 2007-07-31 US disclosed
US-7186781-B2 Fullerene-containing polymer, producing method thereof, and photorefractive composition NITTO DENKO CORPORATION (JP) 2007-03-06 US disclosed