SCHEMBL254570

SCHEMBL254570

N#CC(C#N)=C1CCc2cccc3cccc1c23

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.51
LMNA P02545 1/20 0.51
EGFR P00533 2/20 0.47
ALDH1A1 P00352 6/20 0.41
KDM4E B2RXH2 3/20 0.40
HPGD P15428 2/20 0.40
MCL1 Q07820 2/20 0.38
TYMS P04818 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
PARP1 P09874 1/20 0.37
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
GAA P10253 1/20 0.35
TSHR P16473 2/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 2/20 0.33
HTT P42858 1/20 0.33
MAPK1 P28482 2/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30067531 1.00 HSD17B10 (0.51) HSD17B10LMNAEGFRALDH1A1KDM4E
SCHEMBL30067524 0.85 ALDH1A1 (0.49) HSD17B10LMNAEGFRALDH1A1KDM4E
SCHEMBL10046788 0.84 HSD17B10 (0.49) HSD17B10LMNAEGFRALDH1A1KDM4E
SCHEMBL255282 0.80 EGFR (0.55) EGFRALDH1A1KDM4EHPGDGAA
SCHEMBL30067338 0.80 EGFR (0.55) EGFRALDH1A1KDM4EHPGDGAA
SCHEMBL9970452 0.80 HSD17B10 (0.45) HSD17B10LMNAALDH1A1KDM4EHPGD
SCHEMBL255344 0.75 EGFR (0.62) HSD17B10LMNAEGFRALDH1A1HPGD
SCHEMBL21938550 0.72 ALDH1A1 (0.50) HSD17B10ALDH1A1KDM4EHPGDMCL1
Acenaphthene SCHEMBL27875520 0.71 TSHR (0.55) HSD17B10LMNAALDH1A1KDM4EHPGD
SCHEMBL809325 0.70 CYP2A6 (0.46) EGFRALDH1A1HPGDCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130170016-A1 PHOTOREFRACTIVE DEVICE CONTAINING A CHROMOPHORE-DOPED POLYMER LAYER AND ITS MANUFACTURING METHOD NITTO DENKO CORPORATION (JP) 2013-07-04 US disclosed
US-20130163086-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE BY UTILIZING ELECTROLYTES NITTO DENKO CORPORATION (JP) 2013-06-27 US disclosed
US-20130128339-A1 PHOTOREFRACTIVE COMPOSITION RESPONSIVE TO MULTIPLE LASER WAVELENGTHS ACROSS THE VISIBLE LIGHT SPECTRUM NITTO DENKO CORPORATION (JP) 2013-05-23 US disclosed
WO-2013075050-A1 PHOTOREFRACTIVE DEVICE CONTAINING CARBON NANOTUBE-DOPED POLYMER LAYERS AND ITS MANUFACTURING METHOD NITTO DENKO CORPORATION (JP) 2013-05-23 WO disclosed
EP-1578884-B1 POLYMER, PRODUCING METHOD THEREOF, AND PHOTOREFRACTIVE COMPOSITION NITTO DENKO CORP (JP) 2013-04-24 EP disclosed
US-20120275007-A1 OPTICAL DEVICES FOR MODULATING LIGHT OF PHOTOREFRACTIVE COMPOSITIONS WITH THERMAL CONTROL NITTO DENKO CORPORATION (JP) 2012-11-01 US disclosed
WO-2012112876-A1 PHOTOREFRACTIVE DEVICES HAVING SOL-GEL BUFFER LAYERS AND METHODS OF MANUFACTURING NITTO DENKO CORPORATION (JP) 2012-08-23 WO disclosed
US-8203780-B2 Systems and methods for improving the performance of a photorefractive device NITTO DENKO CORPORATION (JP) 2012-06-19 US disclosed
EP-2261270-B1 Polymer, producing method thereof, and photorefractive composition NITTO DENKO CORP (JP) 2012-05-09 EP disclosed
EP-2434340-A1 Systems and methods for improving the performance of a photorefractive device Nitto Denko Corporation (JP) 2012-03-28 EP disclosed
US-20090197186-A1 OPTICAL DEVICES RESPONSIVE TO BLUE LASER AND METHOD OF MODULATING LIGHT NITTO DENKO CORPORATION (JP) 2009-08-06 US disclosed
US-20090052009-A1 NON-LINEAR OPTICAL DEVICE SENSITIVE TO GREEN LASER NITTO DENKO CORPORATION (JP) 2009-02-26 US disclosed
WO-2008091716-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE NITTO DENKO CORPORATION (JP) 2008-07-31 WO disclosed
US-20080039603-A1 NON-LINEAR OPTICAL DEVICE WITH LONG GRATING PERSISTENCY NITTO DENKO CORPORATION (JP) 2008-02-14 US disclosed
WO-2008013774-A2 NON-LINEAR OPTICAL DEVICE WITH LONG GRATING PERSISTENCY NITTO DENKO CORPORATION (JP) 2008-01-31 WO disclosed
WO-2008013775-A2 NON-LINEAR OPTICAL DEVICE SENSITIVE TO GREEN LASER NITTO DENKO CORPORATION (JP) 2008-01-31 WO disclosed
US-7317058-B2 (Meth)acrylate polymer and non-linear optical device material composition NITTO DENKO CORPORATION (JP) 2008-01-08 US disclosed
WO-2007100369-A2 NON-LINEAR OPTICAL DEVICE MATERIAL COMPOSITION NITTO DENKO CORPORATION (JP) 2007-09-07 WO disclosed
US-7250121-B2 Non-linear optical device material composition NITTO DENKO CORPORATION (JP) 2007-07-31 US disclosed
US-7186781-B2 Fullerene-containing polymer, producing method thereof, and photorefractive composition NITTO DENKO CORPORATION (JP) 2007-03-06 US disclosed