Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.52 |
| ▸ | NOS3 | P29474 | 2/20 | 0.52 |
| ▸ | NOS1 | P29475 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2550616 | 0.94 | NOS3 (0.50) | NOS2NOS3NOS1LMNAKDM4E | |
| SCHEMBL31280277 | 0.94 | NOS3 (0.50) | NOS2NOS3NOS1LMNAKDM4E | |
| SCHEMBL30019258 | 0.92 | KCNH2 (0.48) | NOS2NOS3NOS1LMNAKDM4E | |
| Tetradecane SCHEMBL27660314 | 0.92 | KCNH2 (0.48) | NOS2NOS3NOS1LMNAKDM4E | |
| SCHEMBL27630660 | 0.92 | KCNH2 (0.48) | NOS2NOS3NOS1LMNAKDM4E | |
| SCHEMBL2555626 | 0.92 | KCNH2 (0.48) | NOS2NOS3NOS1LMNAKDM4E | |
| SCHEMBL13337725 | 0.92 | NOS3 (0.55) | NOS2NOS3NOS1LMNAKDM4E | |
| Bromide SCHEMBL9300889 | 0.91 | KCNH2 (0.47) | NOS2NOS3NOS1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL28148327 | 0.91 | KCNH2 (0.47) | NOS2NOS3NOS1LMNAKDM4E | |
| SCHEMBL6560564 | 0.90 | KDM4E (0.44) | NOS2NOS3NOS1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8652452-B2 | 2,4-disubstituted pyridines as perfuming ingredients | FIRMENICH SA (CH) | 2014-02-18 | — | — | US | disclosed |
| EP-2552395-B1 | 2,4-disubstituted pyridines as perfuming ingredients | FIRMENICH & CIE (CH) | 2013-11-13 | — | — | EP | disclosed |
| EP-2552395-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | Firmenich S.A. (CH) | 2013-02-06 | — | — | EP | disclosed |
| US-20130004447-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2013-01-03 | — | — | US | disclosed |
| WO-2011121469-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2011-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130004447-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | P2RX5, P2RX4, C5 | NOS2 927/4885NOS3 819/4885NOS1 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.