SCHEMBL255284

SCHEMBL255284

N#CC(C#N)=C1CC(=C(C#N)C#N)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.40
GAA P10253 1/20 0.40
ALDH1A1 P00352 6/20 0.38
MAPT P10636 4/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
POLB P06746 1/20 0.37
GPR35 Q9HC97 1/20 0.37
HTT P42858 1/20 0.37
KDM4E B2RXH2 1/20 0.35
ESR2 Q92731 1/20 0.32
PIM1 P11309 1/20 0.32
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29619668 1.00 EGFR (0.40) EGFRGAAALDH1A1MAPTKMT2A
SCHEMBL27294468 0.92 EGFR (0.36) EGFRGAAALDH1A1MAPTKMT2A
SCHEMBL14141263 0.88 GAA (0.37) EGFRGAAALDH1A1MAPTKMT2A
SCHEMBL30118004 0.87 MAPT (0.33) EGFRGAAALDH1A1MAPTKMT2A
SCHEMBL30118003 0.87 MAPT (0.33) EGFRGAAALDH1A1MAPTKMT2A
SCHEMBL13301891 0.86 ALDH1A1 (0.42) EGFRGAAALDH1A1MAPTKMT2A
SCHEMBL26722401 0.86 GAA (0.38) EGFRGAAALDH1A1MAPTKMT2A
SCHEMBL29444282 0.86 MAPT (0.38) EGFRGAAALDH1A1MAPTKMT2A
SCHEMBL806906 0.86 MAPT (0.38) EGFRGAAALDH1A1MAPTKMT2A
SCHEMBL30464047 0.84 MAPT (0.37) EGFRGAAALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12023387-B2 NIR-II emissive luminogens THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-07-02 US claimed
WO-2022199140-A1 LIPID DROPLET TARGETED FLUORESCENT DYE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 深圳先进技术研究院 2022-09-29 WO claimed
EP-1362579-B1 Agent for dyeing keratinous fibres HENKEL KGAA (DE) 2006-05-24 EP claimed
EP-1300135-B1 Agent for dyeing keratinous fibres comprising 2-aryliden-indolin-3-one derivatives HENKEL KGAA (DE) 2006-05-03 EP claimed
EP-1434552-A1 METHOD FOR DYEING KERATINOUS FIBRES Henkel Kommanditgesellschaft auf Aktien (DE) 2004-07-07 EP claimed
EP-1433785-A1 Agents for the coloration of keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP claimed
EP-1362579-A1 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-11-19 EP claimed
EP-1002516-B1 Hair dyes containing indan derivatives WELLA AG (DE) 2003-09-24 EP claimed
WO-2003030841-A1 METHOD FOR DYEING KERATINOUS FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1300135-A1 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
US-6231622-B1 MIXTURES; BLUE COLOR WELLA AKTIENGESELLSCHAFT (DE) 2001-05-15 US claimed
EP-1002516-A1 Hair dyes containing indan derivatives Wella Aktiengesellschaft (DE) 2000-05-24 EP claimed
US-5194463-A LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN KODAK COMPANY (US) 1993-03-16 US claimed
JP-1009968-A None JP disclosed
US-12622966-B2 Compound for photothermal cancer therapy, composition including the same, and method for photothermal cancer therapy PUKYONG NATIONAL INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) 2026-05-12 US disclosed
US-20250293254-A1 SECONDARY BATTERY MURATA MANUFACTURING CO., LTD. (JP) 2025-09-18 US disclosed
US-4985395-A Dye-donor element for thermal dye sublimation transfer AGFA-GEVAERT, N.V. (BE) 1991-01-15 US disclosed
EP-0384040-A1 Dye-donor element for thermal dye sublimation transfer AGFA-GEVAERT N.V. (BE) 1990-08-29 EP disclosed
JP-S649968-A 1,3-BIS(DICYANOMETHYLENE)INDANE DERIVATIVE AND PRODUCTION THEREOF SUMITOMO CHEMICAL CO 1989-01-13 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12023387-B2 NIR-II emissive luminogens DBI, UACA, BRI3BP EGFR 2209/4885GAA 2375/4885ALDH1A1 1798/4885
US-12622966-B2 Compound for photothermal cancer therapy, composition including the same, and method for photothermal cancer therapy BRCA1, TP53, MKI67 EGFR 65/4885GAA 2130/4885ALDH1A1 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.