Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.61 |
| ▸ | CTSS | P25774 | 6/20 | 0.61 |
| ▸ | CTSB | P07858 | 2/20 | 0.61 |
| ▸ | CTSL | P07711 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 1/20 | 0.59 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8271187 | 0.93 | CTSK (0.59) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL14632961 | 0.93 | CTSK (0.59) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL25526043 | 0.91 | CTSK (0.58) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL16124527 | 0.91 | CTSK (0.58) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL29830632 | 0.90 | CTSK (0.57) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL30601899 | 0.90 | CTSK (0.57) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL30219144 | 0.90 | CTSK (0.57) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL8661246 | 0.90 | CTSK (0.57) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL29830908 | 0.90 | CTSK (0.57) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL29830683 | 0.90 | CTSK (0.57) | CTSKCTSSCTSBCTSLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151049-A1 | Compounds Useful in HIV Therapy | VIIV HEALTHCARE COMPANY (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151049-A1 | Compounds Useful in HIV Therapy | CCR5, CD4, NPC1 | CTSK 1780/4885CTSS 1280/4885CTSB 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.