Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | PHGDH | O43175 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557226 | 0.83 | USP2 (0.54) | ALDH1A1PHGDHNPSR1LMNAHTR6 | |
| SCHEMBL14194068 | 0.83 | MAPT (0.46) | ALDH1A1PHGDHLMNAGAAMAPT | |
| SCHEMBL13778131 | 0.79 | STS (0.55) | ALDH1A1PHGDHNPSR1LMNAMAPT | |
| SCHEMBL30553379 | 0.79 | PHGDH (0.45) | POLBALDH1A1PHGDHNPSR1LMNA | |
| SCHEMBL14922275 | 0.78 | POLB (0.71) | POLBALDH1A1LMNABCL2A1MAPT | |
| SCHEMBL24712697 | 0.77 | DRD2 (0.69) | ALDH1A1LMNAHTR6MAPTDRD2 | |
| SCHEMBL8275465 | 0.73 | POLB (0.65) | POLBALDH1A1PHGDHBCL2A1MAPT | |
| SCHEMBL360379 | 0.73 | POLB (1.00) | POLBALDH1A1LMNAGAABCL2A1 | |
| SCHEMBL2570869 | 0.73 | HTT (0.43) | POLBALDH1A1GAAMAPTKDM4E | |
| SCHEMBL1481336 | 0.72 | POLB (0.58) | POLBALDH1A1LMNAGAABCL2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |