Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 5/20 | 0.50 |
| ▸ | HTR6 | P50406 | 8/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | EED | O75530 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4825361 | 0.84 | DRD2 (0.62) | DRD2EGFRMAPTMAPK1ADRA1D | |
| SCHEMBL24713023 | 0.81 | DRD2 (0.78) | DRD2LMNAADRA1DADRA1AADRA1B | |
| SCHEMBL3848435 | 0.81 | HTR6 (0.67) | DRD2LMNAMAPTDRD3HTR6 | |
| SCHEMBL14194068 | 0.78 | MAPT (0.46) | DRD2LMNAMAPTKMT2ACYP3A4 | |
| SCHEMBL17290724 | 0.77 | DRD2 (0.44) | DRD2ADRA2CEGFRLMNAMAPT | |
| SCHEMBL2552885 | 0.77 | POLB (0.58) | DRD2LMNAMAPTHTR6CYP3A4 | |
| SCHEMBL28253809 | 0.75 | DRD2 (0.52) | DRD2LMNAKMT2AADRA1DADRA1A | |
| SCHEMBL14355835 | 0.75 | TSHR (0.52) | DRD2ADRA2CEGFRLMNAMAPT | |
| Hydrochloric Acid SCHEMBL3882302 | 0.74 | HTR6 (0.58) | DRD2LMNAMAPTDRD3HTR6 | |
| SCHEMBL29954881 | 0.74 | NOTUM (0.52) | DRD2LMNAMAPTKMT2AEED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220267303-A1 | Compounds and Methods for Treating or Preventing Bacterial Infections | BAYLOR COLLEGE OF MEDICINE | 2022-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267303-A1 | Compounds and Methods for Treating or Preventing Bacterial Infections | OXA1L, MMP8, OGG1 | DRD2 3147/4885ADRA2C 2380/4885EGFR 3759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.