Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.48 |
| ▸ | CKS1B | P61024 | 1/20 | 0.48 |
| ▸ | SKP1 | P63208 | 1/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | SUV39H2 | Q9H5I1 | 7/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25530547 | 0.94 | MAP4K4 (0.49) | PIM1PIM3PIM2CKS1BSKP1 | |
| SCHEMBL25417601 | 0.94 | MAP4K4 (0.49) | PIM1PIM3PIM2CKS1BSKP1 | |
| SCHEMBL30397448 | 0.94 | MAP4K4 (0.49) | PIM1PIM3PIM2CKS1BSKP1 | |
| SCHEMBL25417386 | 0.79 | MAP4K4 (0.46) | PDE10ABTKSUV39H2METMAP4K4 | |
| SCHEMBL25238236 | 0.79 | MAP4K4 (0.46) | PDE10ABTKSUV39H2METMAP4K4 | |
| SCHEMBL25538214 | 0.78 | BTK (0.52) | CKS1BSKP1SKP2PDE10ABTK | |
| SCHEMBL23500781 | 0.77 | CKS1B (0.56) | PIM1PIM3PIM2CKS1BSKP1 | |
| SCHEMBL15222937 | 0.77 | CKS1B (0.56) | PIM1PIM3PIM2CKS1BSKP1 | |
| SCHEMBL25417882 | 0.77 | BTK (0.51) | BTKSUV39H2METCTSKMAP4K4 | |
| SCHEMBL4827630 | 0.75 | GPR119 (0.60) | PIM1PIM3PIM2CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |