Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174302 | 1.00 | MAPK14 (0.34) | MAPK14PARP1PARP2ALDH1A1L3MBTL1 | |
| SCHEMBL23146745 | 0.78 | L3MBTL1 (0.50) | ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL25529136 | 0.74 | MAPK14 (0.40) | MAPK14ALDH1A1L3MBTL1KDM4EGPR119 | |
| SCHEMBL30174170 | 0.74 | MYC (0.36) | MAPK14ALDH1A1L3MBTL1KDM4EHRH3 | |
| SCHEMBL25529134 | 0.74 | L3MBTL1 (0.38) | MAPK14ALDH1A1L3MBTL1KDM4EHRH3 | |
| SCHEMBL25528981 | 0.74 | MYC (0.42) | ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL25227025 | 0.74 | MYC (0.36) | MAPK14ALDH1A1L3MBTL1KDM4EHRH3 | |
| SCHEMBL30174285 | 0.72 | KDM4E (0.36) | MAPK14ALDH1A1L3MBTL1KDM4EHRH3 | |
| SCHEMBL30174233 | 0.72 | TYK2 (0.40) | MAPK14ALDH1A1L3MBTL1KDM4EJAK2 | |
| SCHEMBL25234474 | 0.71 | L3MBTL1 (0.42) | MAPK14L3MBTL1KDM4EGRM1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151003-A1 | COMPOUNDS AND METHODS OF USE | EXELIXIS INC (US) | 2023-05-18 | — | — | US | disclosed |
| US-20230151003-A1 | COMPOUNDS AND METHODS OF USE | EXELIXIS INC (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151003-A1 | COMPOUNDS AND METHODS OF USE | PRKACB, PRKACA, PRKX | MAPK14 307/4885PARP1 1038/4885PARP2 840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.