Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC27A1 | Q6PCB7 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25227025 | 1.00 | MYC (0.36) | MYCNOTUMKMT2APPARGKDM4E | |
| SCHEMBL25529134 | 0.89 | L3MBTL1 (0.38) | PPARGKDM4EGRM5MAPK14ALDH1A1 | |
| SCHEMBL30174285 | 0.87 | KDM4E (0.36) | PPARGKDM4EGRM5MAPK14ALDH1A1 | |
| SCHEMBL30063313 | 0.85 | KDM4E (0.40) | KMT2AKDM4ESMN1; SMN2GRM5MAPK14 | |
| SCHEMBL25533451 | 0.85 | KDM4E (0.40) | KMT2AKDM4ESMN1; SMN2GRM5MAPK14 | |
| SCHEMBL23147891 | 0.84 | NOTUM (0.49) | MYCNOTUMKMT2AKDM4ELMNA | |
| SCHEMBL25528981 | 0.80 | MYC (0.42) | MYCNOTUMKMT2AKDM4EALDH1A1 | |
| SCHEMBL29812420 | 0.80 | HCAR1 (0.41) | MYCNOTUMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL23147208 | 0.80 | HCAR1 (0.41) | MYCNOTUMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL25234474 | 0.78 | L3MBTL1 (0.42) | NOTUMPPARGKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |