Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | KCNK18 | Q7Z418 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30463746 | 0.91 | GSK3B (0.44) | TP53ABCG2GSK3BTAS2R14FLT1 | |
| SCHEMBL22556571 | 0.91 | GSK3B (0.44) | TP53ABCG2GSK3BTAS2R14FLT1 | |
| SCHEMBL22571365 | 0.79 | KDM4E (0.51) | TP53ABCG2GSK3BTAS2R14FLT1 | |
| SCHEMBL22556410 | 0.79 | GSK3B (0.43) | TP53ABCG2GSK3BTAS2R14FLT1 | |
| SCHEMBL22556413 | 0.79 | GSK3B (0.43) | TP53ABCG2GSK3BTAS2R14FLT1 | |
| SCHEMBL30463794 | 0.79 | GSK3B (0.43) | TP53ABCG2GSK3BTAS2R14FLT1 | |
| SCHEMBL22571425 | 0.77 | TP53 (0.37) | TP53ABCG2GSK3BTAS2R14FLT1 | |
| SCHEMBL22571368 | 0.75 | GSK3B (0.45) | TP53ABCG2GSK3BTAS2R14FLT1 | |
| SCHEMBL22571428 | 0.74 | GSK3B (0.47) | TP53ABCG2GSK3BTAS2R14FLT1 | |
| SCHEMBL22556442 | 0.74 | GSK3B (0.42) | TP53ABCG2GSK3BTAS2R14FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11661403-B2 | Oxadiazole compounds | VIVACE THERAPEUTICS, INC. (US) | 2023-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11661403-B2 | Oxadiazole compounds | YAP1, TEAD2, TEAD3 | TP53 4/4885ABCG2 2985/4885GSK3B 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.