Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 19/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 14/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528340 | 0.90 | PARP1 (0.44) | ROCK2ROCK1PARP1 | |
| SCHEMBL25529692 | 0.88 | ROCK2 (0.52) | ROCK2ROCK1 | |
| SCHEMBL25528196 | 0.86 | ROCK2 (0.43) | ROCK2ROCK1PARP1 | |
| SCHEMBL25528343 | 0.85 | PARP1 (0.43) | ROCK2ROCK1PARP1 | |
| SCHEMBL25528200 | 0.81 | ROCK2 (0.40) | ROCK2ROCK1PARP1 | |
| SCHEMBL25531233 | 0.81 | IRAK4 (0.42) | ROCK2ROCK1PARP1 | |
| SCHEMBL25528771 | 0.80 | ROCK2 (0.42) | ROCK2ROCK1PARP1 | |
| SCHEMBL25528201 | 0.80 | ROCK2 (0.39) | ROCK2ROCK1PARP1 | |
| SCHEMBL25528339 | 0.79 | PARP1 (0.41) | ROCK2ROCK1PARP1 | |
| SCHEMBL25529068 | 0.79 | ROCK2 (0.43) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093787-A1 | BENZODIAZEPINE COMPOUND AND APPLICATION THEREOF AS RHO KINASE INHIBITOR | 成都奥睿药业有限公司 | 2023-06-01 | — | — | WO | disclosed |