Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25235574 | 1.00 | CTSK (0.36) | CTSKMAOAMAOBSSTR4SSTR1 | |
| SCHEMBL24037096 | 1.00 | CTSK (0.36) | CTSKMAOAMAOBSSTR4SSTR1 | |
| SCHEMBL24037072 | 0.88 | USP30 (0.36) | CTSKMAOAMAOBSSTR4HRH3 | |
| SCHEMBL31250954 | 0.85 | CYP1A2 (0.36) | CTSKMAOAMAOBHRH3BTK | |
| SCHEMBL20089656 | 0.85 | CTSK (0.45) | CTSKCA1CA2DRD2BTK | |
| SCHEMBL31250822 | 0.84 | CA2 (0.36) | CTSKMAOAMAOBHRH3NFKB1 | |
| SCHEMBL26619909 | 0.81 | GBA1 (0.35) | SSTR4SSTR1DRD2 | |
| SCHEMBL26619907 | 0.81 | GBA1 (0.35) | SSTR4SSTR1DRD2 | |
| SCHEMBL24036902 | 0.77 | CTSK (0.53) | CTSKCA1CA2DRD2BTK | |
| SCHEMBL21584005 | 0.77 | CTSK (0.53) | CTSKCA1CA2DRD2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083283-A1 | DRUG COMBINATION FOR TREATING TUMOR, AND APPLICATION THEREOF | 先声药业有限公司 | 2023-05-19 | — | — | WO | disclosed |