Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2645 | 0.85 | FFAR1 (0.46) | PTPN1FFAR1AKR1B1LTB4R2MYC | |
| SCHEMBL3443 | 0.80 | MYC (0.47) | PTPN1FFAR1AKR1B1MYCWDR5 | |
| SCHEMBL8472443 | 0.79 | LTB4R2 (0.37) | LTB4R2BDKRB1AGTR1AGTR2 | |
| SCHEMBL9674134 | 0.73 | LTB4R2 (0.52) | PTPN1FFAR1AKR1B1LTB4R2MYC | |
| Hydrochloric Acid SCHEMBL9844253 | 0.73 | LTB4R2 (0.47) | PTPN1FFAR1AKR1B1LTB4R2MYC | |
| SCHEMBL9429437 | 0.72 | LTB4R2 (0.48) | PTPN1LTB4R2AGTR1AGTR2 | |
| SCHEMBL3147 | 0.72 | FFAR1 (0.49) | PTPN1FFAR1AKR1B1MYCWDR5 | |
| SCHEMBL6959964 | 0.71 | PTPN1 (0.57) | PTPN1FFAR1AKR1B1MYCWDR5 | |
| SCHEMBL9429769 | 0.71 | LTB4R2 (0.49) | FFAR1AKR1B1LTB4R2AGTR1AGTR2 | |
| SCHEMBL633444 | 0.71 | MME (0.48) | PTPN1FFAR1AKR1B1LTB4R2MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0443983-A1 | Acyl compounds | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |