Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147 | 0.88 | FFAR1 (0.49) | MYCWDR5FFAR1AKR1B1PTPN1 | |
| SCHEMBL2553 | 0.80 | PTPN1 (0.41) | MYCWDR5FFAR1AKR1B1PTPN1 | |
| SCHEMBL6959964 | 0.78 | PTPN1 (0.57) | MYCWDR5FFAR1AKR1B1PTPN1 | |
| SCHEMBL2208 | 0.78 | MYC (0.48) | MYCWDR5FFAR1AKR1B1PTPN1 | |
| SCHEMBL21328307 | 0.77 | RIPK1 (0.47) | PTPN1MEN1ALDH1A1KMT2A | |
| SCHEMBL2226 | 0.76 | MYC (0.46) | MYCWDR5FFAR1AKR1B1PTPN1 | |
| SCHEMBL2870 | 0.76 | MYC (0.47) | MYCWDR5FFAR1AKR1B1PTPN1 | |
| SCHEMBL2132 | 0.76 | MYC (0.47) | MYCWDR5FFAR1AKR1B1PTPN1 | |
| SCHEMBL7435402 | 0.75 | ESR2 (0.56) | MYCWDR5FFAR1AKR1B1ESR2 | |
| SCHEMBL2645 | 0.74 | FFAR1 (0.46) | MYCWDR5FFAR1AKR1B1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0443983-A1 | Acyl compounds | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |