Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553 | 0.85 | PTPN1 (0.41) | FFAR1AKR1B1PTPN1MMEMYC | |
| SCHEMBL3147 | 0.84 | FFAR1 (0.49) | FFAR1AKR1B1PTPN1MMEMYC | |
| SCHEMBL2410 | 0.80 | TNKS (0.35) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL11832786 | 0.77 | FFAR1 (0.49) | FFAR1AKR1B1PTPN1MMEEGLN1 | |
| SCHEMBL11845649 | 0.76 | FFAR1 (0.50) | FFAR1AKR1B1PTPN1MMEEGLN1 | |
| SCHEMBL3443 | 0.74 | MYC (0.47) | FFAR1AKR1B1PTPN1MMEMYC | |
| SCHEMBL6961953 | 0.74 | FFAR1 (0.54) | FFAR1AKR1B1PTPN1MMEMYC | |
| SCHEMBL14004740 | 0.71 | FFAR1 (0.48) | FFAR1AKR1B1PTPN1MMEMYC | |
| SCHEMBL2317 | 0.71 | FFAR1 (0.48) | FFAR1AKR1B1PTPN1MMEMYC | |
| SCHEMBL27453802 | 0.71 | FFAR1 (0.53) | FFAR1AKR1B1PTPN1MMEMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |