SCHEMBL2553012

SCHEMBL2553012

C=CC(=O)N(C)C(CCCCC)CS(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.37
ZDHHC20 Q5W0Z9 4/20 0.35
ZDHHC2 Q9UIJ5 3/20 0.35
TSHR P16473 2/20 0.31
GPR84 Q9NQS5 3/20 0.31
CA1 P00915 2/20 0.31
FFAR1 O14842 1/20 0.31
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
LCK P06239 1/20 0.30
PPARD Q03181 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2557519 0.95 TSHR (0.35) TP53ZDHHC20ZDHHC2TSHRHPGD
SCHEMBL14938071 0.89
SCHEMBL14937663 0.83
Propene SCHEMBL28087908 0.80 TP53 (0.40) TP53ZDHHC20ZDHHC2GPR84CA1
Acrylic Acid SCHEMBL28316171 0.80 CA1 (0.38) TP53ZDHHC20ZDHHC2TSHRGPR84
SCHEMBL2725283 0.79 TP53 (0.37) TP53ZDHHC20ZDHHC2TSHRGPR84
Propene SCHEMBL28234263 0.79 TP53 (0.39) TP53ZDHHC20ZDHHC2MAPT
SCHEMBL27723105 0.77 TP53 (0.46) TP53ZDHHC20ZDHHC2GPR84CA1
SCHEMBL2555169 0.77 FDPS (0.42) ZDHHC20ZDHHC2
SCHEMBL23000969 0.76 TP53 (0.44) TP53ZDHHC20ZDHHC2GPR84CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180346804-A1 CROSSLINKED POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL AND LACTAM MOIETIES AND SULFONIC ACID/SULFONATE COMONOMERS, COMPOSITIONS THEREOF, AND APPLICATIONS THEREOF HERCULES LLC 2018-12-06 US claimed
EP-3377034-A1 CROSSLINKED POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL AND LACTAM MOIETIES AND SULFONIC ACID/SULFONATE COMONOMERS, COMPOSITIONS THEREOF, AND APPLICATIONS THEREOF Hercules LLC (US) 2018-09-26 EP claimed
US-9493598-B2 Polymers having acid and amide moieties, and uses thereof ISP INVESTMENTS LLC (US) 2016-11-15 US claimed
US-20130261275-A1 NON-HOMOPOLYMERS EXHIBITING GAS HYDRATE INHIBITION, SALT TOLERANCE AND HIGH CLOUD POINT ISP INVESTMENTS INC. (US) 2013-10-03 US claimed
US-20130123147-A1 POLYMERS HAVING ACID AND AMIDE MOIETIES, AND USES THEREOF ISP INVESTMENTS INC. (US) 2013-05-16 US claimed
WO-2012054569-A2 NON-HOMOPOLYMERS EXHIBITING GAS HYDRATE INHIBITION, SALT TOLERANCE AND HIGH CLOUD POINT ISP INVESTMENTS INC. (US) 2012-04-26 WO claimed
US-11001751-B2 Crosslinked polymers derived from monomers having acryloyl and lactam moieties and sulfonic acid/sulfonate comonomers, compositions thereof, and applications thereof HERCULES LLC (US) 2021-05-11 US disclosed
US-20180346804-A1 CROSSLINKED POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL AND LACTAM MOIETIES AND SULFONIC ACID/SULFONATE COMONOMERS, COMPOSITIONS THEREOF, AND APPLICATIONS THEREOF HERCULES LLC 2018-12-06 US disclosed
US-9493598-B2 Polymers having acid and amide moieties, and uses thereof ISP INVESTMENTS LLC (US) 2016-11-15 US disclosed
US-20130123147-A1 POLYMERS HAVING ACID AND AMIDE MOIETIES, AND USES THEREOF ISP INVESTMENTS INC. (US) 2013-05-16 US disclosed
WO-2011130370-A1 POLYMERS HAVING ACID AND AMIDE MOIETIES, AND USES THEREOF ISP INVESTMENTS INC. (US) 2011-10-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11001751-B2 Crosslinked polymers derived from monomers having acryloyl and lactam moieties and sulfonic acid/sulfonate comonomers, compositions thereof, and applications thereof CAD, STS, COASY TP53 2988/4885ZDHHC20 383/4885ZDHHC2 341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.