Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13176930 | 0.78 | PLA2G7 (0.50) | PLA2G7ELANEMEN1KMT2AMAPT | |
| SCHEMBL10343150 | 0.76 | PLA2G7 (0.47) | PLA2G7ELANEMEN1KMT2AMAPT | |
| SCHEMBL1755255 | 0.74 | PLA2G7 (0.47) | PLA2G7ELANEMEN1KMT2AMAPT | |
| SCHEMBL277914 | 0.74 | PLA2G7 (0.67) | PLA2G7ELANEMEN1KMT2AMAPT | |
| SCHEMBL10592032 | 0.74 | PLA2G7 (0.47) | PLA2G7MEN1KMT2AHPGDTP53 | |
| SCHEMBL277747 | 0.73 | ELANE (0.52) | PLA2G7ELANEMEN1KMT2AMAPT | |
| SCHEMBL29354513 | 0.72 | ELANE (0.42) | PLA2G7ELANEMEN1KMT2AMAPT | |
| SCHEMBL321560 | 0.71 | PLA2G7 (0.61) | PLA2G7ELANEKMT2AHPGDHSD11B1 | |
| SCHEMBL27781528 | 0.71 | PLA2G7 (0.52) | PLA2G7ELANEMEN1KMT2AMAPT | |
| SCHEMBL27781527 | 0.71 | PLA2G7 (0.52) | PLA2G7ELANEMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023089052-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR DISEASES OF THE CNS | Samsara Therapeutics Inc. (US) | 2023-05-25 | — | — | WO | disclosed |
| EP-4183449-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2023-05-24 | — | — | EP | disclosed |