Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2552976 | 0.89 | MET (0.46) | METCYP3A4 | |
| SCHEMBL2553888 | 0.85 | MET (0.57) | METCYP3A4 | |
| SCHEMBL2553079 | 0.83 | MET (0.57) | METCYP3A4 | |
| SCHEMBL2550397 | 0.83 | MET (0.55) | METCYP3A4 | |
| SCHEMBL2549722 | 0.83 | MET (0.59) | METCYP3A4 | |
| SCHEMBL2578572 | 0.83 | MET (0.56) | METCYP3A4 | |
| SCHEMBL2549101 | 0.83 | MET (0.56) | METCYP3A4 | |
| SCHEMBL2570392 | 0.83 | MET (0.63) | METCYP3A4 | |
| SCHEMBL2576078 | 0.82 | MET (0.59) | METCYP3A4 | |
| SCHEMBL2548814 | 0.82 | MET (0.58) | METCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121223-A1 | 6-(ALKYL- OR CYCLOALKYL-TRIAZOLOPYRIDAZINE-SULFANYL) BENZOTHIAZOLE DERIVATIVES: PREPARATION, APPLICATION AS MEDICAMENTS AND USE AS MET INHIBITORS | SANOFI-AVENTIS (FR) | 2011-10-06 | — | — | WO | claimed |
| WO-2011121223-A1 | 6-(ALKYL- OR CYCLOALKYL-TRIAZOLOPYRIDAZINE-SULFANYL) BENZOTHIAZOLE DERIVATIVES: PREPARATION, APPLICATION AS MEDICAMENTS AND USE AS MET INHIBITORS | SANOFI-AVENTIS (FR) | 2011-10-06 | — | — | WO | disclosed |