SCHEMBL25534725

SCHEMBL25534725

c1ccc(-c2nc(-c3ccccc3-c3ccccc3)cc(-c3ccc(-c4ccc(-c5ccc6c(c5)C(c5ccccc5)(c5ccccc5)c5ccccc5-6)cc4)c4ccccc34)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 13/20 0.39
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
MAPT P10636 2/20 0.35
NTSR1 P30989 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
LMNA P02545 2/20 0.34
KDM4E B2RXH2 1/20 0.34
OPRK1 P41145 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAOB P27338 2/20 0.34
POLB P06746 1/20 0.33
MAOA P21397 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25534833 0.97 PDK2 (0.38) PDK2MEN1KMT2AMAPTNTSR1
SCHEMBL25534944 0.96 PDK2 (0.37) PDK2MEN1KMT2AMAPTNTSR1
SCHEMBL25534612 0.96 MEN1 (0.36) PDK2MEN1KMT2AMAPTNTSR1
SCHEMBL25534821 0.96 PDK2 (0.37) PDK2MEN1KMT2AMAPTNTSR1
SCHEMBL25535053 0.95 PDK2 (0.38) PDK2MEN1KMT2AMAPTNTSR1
SCHEMBL25534767 0.95 PDK2 (0.35) PDK2MEN1KMT2AMAPTNTSR1
SCHEMBL25534853 0.95 MEN1 (0.41) PDK2MEN1KMT2AMAPTNTSR1
SCHEMBL25534856 0.95 MEN1 (0.41) PDK2MEN1KMT2AMAPTNTSR1
SCHEMBL25534737 0.95 MEN1 (0.41) PDK2MEN1KMT2AMAPTNTSR1
SCHEMBL25534727 0.95 MEN1 (0.41) PDK2MEN1KMT2AMAPTNTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE PIEZO1, LEF1, L1CAM PDK2 1828/4885MEN1 267/4885KMT2A 1094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.