SCHEMBL255356

SCHEMBL255356

C#Cc1ccc(C(=O)OC)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.57
CA2 P00918 3/20 0.57
CA12 O43570 2/20 0.57
CA7 P43166 2/20 0.57
CA9 Q16790 2/20 0.57
CA14 Q9ULX7 2/20 0.57
TDP1 Q9NUW8 1/20 0.57
MAPT P10636 4/20 0.55
TSHR P16473 1/20 0.54
ALDH1A1 P00352 1/20 0.52
PTPN11 Q06124 1/20 0.51
LOXL2 Q9Y4K0 1/20 0.50
RAB9A P51151 3/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
HPGD P15428 1/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrogen SCHEMBL25320505 0.96 CA1 (0.53) CA1CA2CA12CA7CA9
SCHEMBL7733739 0.94 CA1 (0.53) CA1CA2CA12CA7CA9
SCHEMBL6132152 0.94 CA1 (0.52) CA1CA2CA12CA7CA9
SCHEMBL6132134 0.91 CA1 (0.56) CA1CA2CA12CA7CA9
Methyl Benzoate SCHEMBL28358400 0.86 TSHR (0.70) CA1CA2CA12CA7CA9
SCHEMBL31474032 0.83 TDP1 (0.45) CA1CA2CA12CA7CA9
SCHEMBL69268 0.83 PTPN11 (0.69) CA1CA2CA12CA7CA9
SCHEMBL23600 0.82 CA1 (0.80) CA1CA2CA12CA7CA9
SCHEMBL28993944 0.82 CA1 (0.80) CA1CA2CA12CA7CA9
SCHEMBL13245026 0.81 PTPN11 (0.54) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 645 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114878542-B Be used for simultaneously detecting intracellular Cu of mitochondria+And Cu2+Surface-enhanced Raman spectrum probe of (2), preparation and application thereof 华东师范大学 2025-02-11 CN claimed
CN-118479973-A Preparation method of 1-naphthylamine compound 西北工业大学 2024-08-13 CN claimed
CN-118388325-A Preparation method of 1-naphthol compound 西北工业大学 2024-07-26 CN claimed
US-11891409-B2 Trifluoromethyl alkenylphosphonate and preparation method therefor SOOCHOW UNIVERSITY (CN) 2024-02-06 US claimed
US-11814462-B2 Functionalized cyclic polymers and methods of preparing same UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-11-14 US claimed
CN-116514651-B Amphiphilic aggregation-induced emission material fluorescent probe and application thereof 北京市疾病预防控制中心 2023-09-05 CN claimed
CN-116514651-A Amphiphilic aggregation-induced emission material fluorescent probe and application thereof 北京市疾病预防控制中心 2023-08-01 CN claimed
CN-111592607-B Application of covalent organic framework material of supported rhodium catalyst in alkyne polymerization 北京理工大学 2023-06-20 CN claimed
CN-116237081-A Wrapped Pd-Ni bimetallic catalyst, catalyst preparation method and application 东南大学 2023-06-09 CN claimed
CN-114702437-B Sonogashira coupling method for heteroaryl phosphonium salt and terminal alkyne 南京工业大学 2023-05-30 CN claimed
CN-108329347-B Method for preparing β -chloroalkenylphosphono derivatives 苏州大学 2020-05-01 CN claimed
CN-110590847-A Process for preparing 2,2' - (1, 4-phenylene) bis (1-phenylphosphine isoindole-1-oxide) 苏州大学 2019-12-20 CN claimed
CN-110577556-A benzophosphandole derivative and preparation method thereof 苏州大学 2019-12-17 CN claimed
CN-109096336-B A kind of preparation method and application of benzo phospha naphthalene derivatives 南通纺织丝绸产业技术研究院 2019-09-27 CN claimed
CN-109096330-A A kind of trifluoromethyl alkenyl phosphonate and preparation method thereof 苏州大学 2018-12-28 CN claimed
CN-109096336-A A kind of preparation method and application of benzo phospha naphthalene derivatives 南通纺织丝绸产业技术研究院 2018-12-28 CN claimed
CN-109096337-A Phosphoheteroandole derivative, benzophosphoheteroandole derivative and preparation method thereof 苏州大学 2018-12-28 CN claimed
EP-2629777-B1 BICYCLIC DIAMINES AS JANUS KINASE INHIBITORS MERCK SHARP & DOHME (US) 2018-12-19 EP claimed
EP-3051946-B1 USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AG (DE) 2017-11-29 EP claimed
EP-0050428-A1 Ethynylated aromatic compounds and process for making same Hughes Aircraft Company (US) 1982-04-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891409-B2 Trifluoromethyl alkenylphosphonate and preparation method therefor AGPS, INPP5B, INPPL1 CA1 2203/4885CA2 1875/4885CA12 2553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.