SCHEMBL25535951

SCHEMBL25535951

c1cc(-c2ccc3c(c2)sc2ccccc23)cc(N(c2ccccc2-c2ccc3ccccc3c2)c2ccccc2-c2ccc3sc4ccccc4c3c2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR5 Q9H228 8/20 0.36
S1PR4 O95977 6/20 0.36
ALOX5 P09917 1/20 0.34
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
GSTP1 P09211 1/20 0.31
GPR3 P46089 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
PIM3 Q86V86 1/20 0.30
POLB P06746 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
F9 P00740 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25535958 1.00 S1PR5 (0.36) S1PR5S1PR4ALOX5ALDH1A1MAPT
SCHEMBL25535415 0.98 S1PR5 (0.36) S1PR5S1PR4ALOX5ALDH1A1MAPT
SCHEMBL25536251 0.98 S1PR5 (0.36) S1PR5S1PR4ALOX5ALDH1A1MAPT
SCHEMBL25558063 0.98 S1PR5 (0.36) S1PR5S1PR4ALOX5ALDH1A1MAPT
SCHEMBL25535940 0.97 S1PR5 (0.38) S1PR5S1PR4ALOX5HSD17B1HSD17B2
SCHEMBL25535968 0.97 S1PR5 (0.38) S1PR5S1PR4ALOX5ALDH1A1MAPT
SCHEMBL24963120 0.95 S1PR5 (0.35) S1PR5S1PR4ALOX5ALDH1A1MAPT
SCHEMBL25535146 0.95 S1PR5 (0.35) S1PR5S1PR4ALOX5ALDH1A1MAPT
SCHEMBL25534404 0.95 S1PR5 (0.36) S1PR5S1PR4ALOX5ALDH1A1MAPT
SCHEMBL24964710 0.94 S1PR5 (0.39) S1PR5S1PR4ALOX5HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230172058-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed
US-20230172058-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172058-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE LEF1, PIEZO1, ELAVL1 S1PR5 4533/4885S1PR4 3989/4885ALOX5 845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.