Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311123 | 0.79 | ESR1 (0.34) | ALDH1A1LMNACYP2A6GAAMAPT | |
| SCHEMBL2550741 | 0.79 | LMNA (0.46) | ALDH1A1TDP1LMNASMN1; SMN2KMT2A | |
| SCHEMBL2542920 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TDP1LMNASMN1; SMN2CYP2A6 | |
| SCHEMBL15330263 | 0.79 | CYP2A6 (0.44) | ALDH1A1TDP1LMNASMN1; SMN2CYP2A6 | |
| SCHEMBL4171846 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TDP1LMNASMN1; SMN2CYP2A6 | |
| SCHEMBL4167184 | 0.79 | CYP2A6 (0.44) | ALDH1A1TDP1SMN1; SMN2CYP2A6GAA | |
| SCHEMBL2561545 | 0.79 | ESR1 (0.34) | ALDH1A1LMNATP53HPGDESR1 | |
| SCHEMBL544445 | 0.78 | TSHR (0.46) | ALDH1A1LMNASMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL9489967 | 0.78 | TSHR (0.46) | ALDH1A1LMNASMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL2554823 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TDP1GAANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| CN-110183435-B | Oxazole drug molecule for hospital sterilization and preparation method thereof | 河南科技大学第一附属医院 | 2020-02-07 | — | — | CN | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |
| US-4228097-A | Method of preparing α-hydroxymethylene nitriles | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1980-10-14 | — | — | US | disclosed |