Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 4/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.35 |
| ▸ | TTK | P33981 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3971277 | 0.95 | MEN1 (0.44) | MEN1KMT2AKDM4EMAPTTHRB | |
| SCHEMBL29714346 | 0.95 | MEN1 (0.44) | MEN1KMT2AKDM4EMAPTTHRB | |
| SCHEMBL29714341 | 0.95 | MEN1 (0.44) | MEN1KMT2AKDM4EMAPTTHRB | |
| SCHEMBL3971391 | 0.82 | HCAR1 (0.34) | FGFR4ADORA2A | |
| SCHEMBL31139435 | 0.80 | FGFR4 (0.48) | MEN1KMT2AKDM4EMAPTFGFR4 | |
| SCHEMBL3967401 | 0.80 | FGFR4 (0.48) | MEN1KMT2AKDM4EMAPTFGFR4 | |
| SCHEMBL24170053 | 0.78 | FGFR4 (0.34) | MEN1KMT2AKDM4EMAPTTHRB | |
| SCHEMBL25538730 | 0.78 | FGFR4 (0.35) | MEN1KMT2AKDM4EMAPTTHRB | |
| SCHEMBL22419389 | 0.77 | MEN1 (0.38) | MEN1KMT2AKDM4EMAPTHPGD | |
| SCHEMBL30278827 | 0.77 | FGFR4 (0.38) | MEN1KMT2AFGFR4PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174550-A1 | IDH MUTANT INHIBITOR AND USE THEREOF | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2023-06-08 | — | — | US | disclosed |
| US-20230174550-A1 | IDH MUTANT INHIBITOR AND USE THEREOF | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174550-A1 | IDH MUTANT INHIBITOR AND USE THEREOF | IDH1, IDH3A, IDH3B | MEN1 1178/4885KMT2A 335/4885KDM4E 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.