SCHEMBL25539404

SCHEMBL25539404

c1ccc(-c2ccc([Si](c3ccccc3)(c3ccccc3)c3cc(-c4ccccc4)c(-n4c5ccccc5c5cc(-c6ccc7c(c6)c6ccccc6n7-c6c(-c7ccccc7)cccc6-c6ccccc6)ccc54)c(-c4ccccc4)c3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSPO P30536 3/20 0.36
MAPK14 Q16539 1/20 0.34
NPY5R Q15761 1/20 0.32
DNM1 Q05193 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PIK3CA P42336 1/20 0.31
DUSP3 P51452 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25539395 0.97 MAPK14 (0.35) TSPOMAPK14NPY5RDNM1KDM4E
SCHEMBL25539397 0.96 TSPO (0.35) TSPOMAPK14NPY5RDNM1KDM4E
SCHEMBL25539408 0.96 TSPO (0.35) TSPOMAPK14NPY5RDNM1KDM4E
SCHEMBL25539000 0.96 TSPO (0.38) TSPOMAPK14NPY5RDNM1KDM4E
SCHEMBL25539401 0.95 TSPO (0.34) TSPOMAPK14NPY5RDNM1
SCHEMBL25538990 0.95 TSPO (0.38) TSPOMAPK14NPY5RDNM1KDM4E
SCHEMBL25538995 0.94 TSPO (0.36) TSPOMAPK14NPY5RDNM1KDM4E
SCHEMBL25539003 0.94 TSPO (0.36) TSPOMAPK14NPY5RDNM1KDM4E
SCHEMBL25539385 0.92 ATM (0.38) TSPOMAPK14NPY5RDNM1KDM4E
SCHEMBL25539548 0.91 MAPK14 (0.32) TSPOMAPK14KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND CRY1, CYP1A1, NQO1 TSPO 1897/4885MAPK14 3606/4885NPY5R 3574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.